The action manga GOLGO 13, created by Takao Salto, is named after its lead character: an assassin.
The series was created in 1968, sold over 200 million copies, and has been adapted into four feature films (two live-action and two animated), a TV series, and five video games. It is the longest running continuously published manga series.
From Kyodo News, here is a celebration of GOLGO 13 with, I think, Mr. Salto and others. It's in Japanese, so I have to guess at some of this.
And just look at the wall of GOLGO 13 albums. Wow!
GOLGO 13 Wikipedia page here.